The Project has archival and research partnerships with the Missouri History Museum (MHM), the State Historical Society of Missouri (SHSM), which has a resource center at the University of Missouri-St. Louis, and Washington University in St. Louis. The Project made an operational decision to work with current archives in the region instead of trying to create its own archives.
- Missouri History Museum: The museum currently has a LGBT exhibit in its "Seeking St. Louis" display area on the second floor. MHM also has several LGBT items in its archives. The Project and MHM are collaborating on several LGBT collecting intitiatives and programs.
- State Historical Society of Missouri: In October of 1987 the Community Liaison for Education and Research (C.L.E.A.R.), a member organization of Challenge Metro (formerly the St. Louis Gay and Lesbian Community Services), began an ambitious effort. This idea consisted of collecting the history of the lesbian and gay community in St. Louis, and was to be called the Lesbian and Gay Archives. The nucleus of the original archives was a large collection of periodicals, clippings, flyers, and brochures donated by the owner of Our World Too Bookstore, Bill Cordes. After an initial surge of activity, the archives were placed in the care of Fredric Rissover. He continued to collect material and was assisted by Bill Cordes. In the summer of 1991, Fredric made arrangements to place the collection with the Western Historical Manuscripts Collection (WHMC) at the University of Missouri-St. Louis. WHMC is now under the auspices of the SHSM. Over the years, hundreds of additional LGBT items have been donated to WHMC, including material by noted local LGBT activist Lisa Wagaman, and others.
- Washington University in St. Louis: Primary and secondary sources about LGBT history at Washington University and in the St. Louis region.
The Project's archival relationships assures artifact donors that items are properly conserved and are accessible to the general public for research.